Chapter 4 develops LIR as an applied categorial ontology, based a view of the fundamental dualities of energy, and hence of reality, as inherent in the effective quantum field description of quantum phenomena. The categories of a New Energy Ontology (NEO) are established, including the essential categories of Dynamic Opposition, Process and T-state (emergent included middle) and Subject-Object that are both formal and physically meaningful. The categories are shown to fit the LIR axioms and the need suggested to view most important, inter-active physical, biological and cognitive phenomena as instantiating the category of Non-Separability, related but not identical to the existence of non-separability at the quantum level of reality. An initial discussion of LIR as an interpreted system is given that looks ahead to the core thesis of LIR.